IPEN is coordinated via Hubs in eight regions: Anglophone Africa; Francophone Africa; Central, Western & (sections of) Eastern Europe (CEWE); a portion of Eastern Europe, the Caucasus & Central Asia (EECCA); Latin America; Middle East & North Africa (MENA); South Asia; and Southeast Asia. The Regional Hubs, operating in most UN languages, coordinate and communicate with IPEN Participating Organizations in their geographic regions, and report to the Network on the regions' needs, activities, and perspectives.

• Anglophone Africa
• Central, Eastern and Western Europe
• Eastern Europe, Caucasus, Central Asian (EECCA) Countries
• Francophone Africa
• Latin America and the Caribbean
• Middle East and North Africa (MENA)
• South Asia
• Southeast and East Asia